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Dorothy M Morré Selected Research

hydroquinone (Esoterica)

1/2014ENOX2 target for the anticancer isoflavone ME-143.
10/2010Essential role of copper in the activity and regular periodicity of a recombinant, tumor-associated, cell surface, growth-related and time-keeping hydroquinone (NADH) oxidase with protein disulfide-thiol interchange activity (ENOX2).
12/2008Cell size increased in tissues from transgenic mice overexpressing a cell surface growth-related and cancer-specific hydroquinone oxidase, tNOX, with protein disulfide-thiol interchange activity.
10/2007Alternative splicing as the basis for specific localization of tNOX, a unique hydroquinone (NADH) oxidase, to the cancer cell surface.
1/2007Antisense experiments demonstrate an exon 4 minus splice variant mRNA as the basis for expression of tNOX, a cancer-specific cell surface protein.
1/2007ECTO-NOX target for the anticancer isoflavene phenoxodiol.
1/2004tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate.
5/2002Monoclonal antibody to a cancer-specific and drug-responsive hydroquinone (NADH) oxidase from the sera of cancer patients.
3/2002Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface.

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Dorothy M Morré Research Topics

Disease

34Neoplasms (Cancer)
01/2016 - 03/2002
5Atherosclerosis
04/2010 - 01/2003
5Carcinoma (Carcinomatosis)
01/2007 - 07/2003
2Mesothelioma
01/2016 - 07/2003
2Malignant Mesothelioma
01/2016 - 01/2016
2Prostatic Neoplasms (Prostate Cancer)
05/2009 - 07/2005
1Asbestosis
01/2016
1Uterine Cervical Neoplasms (Cancer of the Cervix)
11/2011
1Breast Neoplasms (Breast Cancer)
11/2011
1Infections
11/2011
1Coronary Artery Disease (Coronary Atherosclerosis)
09/2011
1Adenocarcinoma
08/2010
1Carcinogenesis
06/2010
1Actinic Keratosis
01/2009
1Carcinoma in Situ
01/2009
1Depressive Disorder (Melancholia)
06/2008
1Body Weight (Weight, Body)
11/2006
1Neoplasm Metastasis (Metastasis)
07/2005
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2003

Drug/Important Bio-Agent (IBA)

22Proteins (Proteins, Gene)FDA Link
01/2016 - 05/2002
15NADH oxidaseIBA
09/2011 - 03/2002
11TeaIBA
01/2014 - 05/2003
10tumor-associated NADH oxidaseIBA
01/2016 - 02/2003
10DisulfidesIBA
01/2014 - 05/2002
10Sulfhydryl Compounds (Thiols)IBA
01/2014 - 05/2002
9hydroquinone (Esoterica)FDA Link
01/2014 - 03/2002
7Pharmaceutical PreparationsIBA
05/2009 - 05/2002
6phenoxodiolIBA
08/2011 - 01/2005
6NAD (NADH)IBA
08/2011 - 05/2002
5Membrane Proteins (Integral Membrane Proteins)IBA
09/2011 - 01/2006
5Oxidoreductases (Dehydrogenase)IBA
08/2010 - 05/2003
5Catechin (Z 7300)IBA
01/2008 - 05/2003
4Lipoproteins (Lipoprotein)IBA
09/2011 - 01/2003
3AntioxidantsIBA
09/2011 - 06/2005
3quinone (benzoquinone)IBA
11/2006 - 01/2003
3Capsaicin (Zostrix)FDA Link
07/2005 - 01/2004
2AsbestosIBA
01/2016 - 01/2016
2Capsules (Microcapsules)IBA
01/2014 - 01/2006
2coenzyme Q10 (CoQ10)IBA
09/2011 - 01/2006
2LDL Lipoproteins (beta Lipoproteins)IBA
09/2011 - 04/2010
2CopperIBA
10/2010 - 12/2008
2EnzymesIBA
05/2009 - 05/2003
2Messenger RNA (mRNA)IBA
10/2007 - 01/2007
2Biological ProductsIBA
08/2005 - 06/2005
2Cisplatin (Platino)FDA LinkGeneric
07/2005 - 01/2005
2Doxorubicin (Adriamycin)FDA LinkGeneric
01/2005 - 07/2003
1IsoflavonesIBA
01/2014
1ME-143IBA
01/2014
1Indicators and Reagents (Reagents)IBA
12/2013
1AlbuminsIBA
11/2011
1RNA (Ribonucleic Acid)IBA
11/2011
1Superoxides (Superoxide)IBA
09/2011
1ubiquinolIBA
08/2010
1Olive OilIBA
06/2010
1Fatty Acids (Saturated Fatty Acids)IBA
06/2010
1Linolenic AcidsIBA
06/2010
1Oleic Acid (Oleate)IBA
06/2010
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
06/2010
1Fish OilsIBA
06/2010
1NADPH Oxidases (NAD(P)H oxidase)IBA
06/2010
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
06/2010
1Omega-6 Fatty Acids (Omega 6 Fatty Acids)IBA
06/2010
1Docosahexaenoic AcidsIBA
06/2010
1ElastinIBA
04/2010
1CollagenIBA
04/2010
1oxidized low density lipoproteinIBA
04/2010
1Ointments (Pastes)IBA
01/2009
1Adenine NucleotidesIBA
12/2008
1LithiumIBA
06/2008
1Protein Isoforms (Isoforms)IBA
01/2008
1Antisense OligonucleotidesIBA
01/2007
1PolyphenolsIBA
11/2006
1Drinking WaterIBA
11/2006
1Capsibiol-TIBA
07/2005
1Paclitaxel (Taxol)FDA LinkGeneric
07/2005
1Cyanides (Isocyanides)IBA
05/2005
1DNA (Deoxyribonucleic Acid)IBA
01/2004
1Hormones (Hormone)IBA
02/2003
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
02/2003
1Coenzymes (Enzyme Cofactors)IBA
01/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2003
1Immune Sera (Antisera)IBA
05/2002
1EpitopesIBA
05/2002
1Monoclonal AntibodiesIBA
05/2002

Therapy/Procedure

3Therapeutics
06/2010 - 01/2008
1Injections
07/2006
1Radiotherapy
07/2003
1Drug Therapy (Chemotherapy)
07/2003